Fitness Volt
  • News
    • Bodybuilding
    • Strongman
    • Powerlifting
    • Armwrestling
    • CrossFit
    • Results
    • Arnold Classic
    • Mr. Olympia
    • 2025 WSM
  • Workouts
    • Training
    • Workout Plans
    • Celebrity Workouts
    • Training Programs
    • Mastering The Deadlift
  • Exercise Guides
    • Muscle Groups
    • Arms
    • Back
    • Chest
    • Core
    • Legs and Glutes
    • Mobility & Stretching
    • Shoulders
    • Yoga
  • Nutrition
    • Diet
    • Fasting
    • Diet Plans
    • Nutrition Tips
    • Supplements
    • Reviews
    • Food Facts
  • Calculators
  • More
    • Forum
    • Strength Standards
    • DIY
    • Profiles
    • Motivation
    • Videos
    • MMA
No Result
View All Result
Fitness Volt
  • News
    • Bodybuilding
    • Strongman
    • Powerlifting
    • Armwrestling
    • CrossFit
    • Results
    • Arnold Classic
    • Mr. Olympia
    • 2025 WSM
  • Workouts
    • Training
    • Workout Plans
    • Celebrity Workouts
    • Training Programs
    • Mastering The Deadlift
  • Exercise Guides
    • Muscle Groups
    • Arms
    • Back
    • Chest
    • Core
    • Legs and Glutes
    • Mobility & Stretching
    • Shoulders
    • Yoga
  • Nutrition
    • Diet
    • Fasting
    • Diet Plans
    • Nutrition Tips
    • Supplements
    • Reviews
    • Food Facts
  • Calculators
  • More
    • Forum
    • Strength Standards
    • DIY
    • Profiles
    • Motivation
    • Videos
    • MMA
No Result
View All Result
Fitness Volt
No Result
View All Result
Home » Muscle Science

What Is Muscle Hypertrophy And Why It’s Important For You To Know

Train for hypertrophy if you want optimal muscle growth and strength gains!

Written by Matthew Magnante, ACE

Last Updated on25 March, 2020 | 12:18 PM EDT

Add us on Google

Ever wondered about the scientific name for muscle growth? You probably guessed it by now but yes… it’s called “muscle hypertrophy”.

There are potentially two types of hypertrophy that you should be aware of – Sarcoplasmic (fluid and glycogen increase) and myofibrillar hypertrophy (myofibril size increase). Since the goal of most athletes and regular fitness fanatics is increasing hypertrophy and strength, it’s helpful to know how the process works.

Although the exact science of muscle growth has still not yet been concluded, we generally know what it takes to achieve hypertrophy through training, nutrition, and other muscle-promoting factors.

So What Exactly Is Hypertrophy?

Well… we already know it’s an increase in muscle volume and mass.

But… to dig deeper, let’s talk about the two likely processes of hypertrophy.

Get Fitter, Faster

Level Up Your Fitness: Join our 💪 strong community in Fitness Volt Newsletter. Get daily inspiration, expert-backed workouts, nutrition tips, the latest in strength sports, and the support you need to reach your goals. Subscribe for free!

Please wait...
You're In! Let's Crush Your Fitness Goals Together

Expect expert-backed workouts, nutrition advice, the latest in strength sports, and a whole lot of motivation heading your way.

Sarcoplasmic Hypertrophy

Sarcoplasmic hypertrophy is explained as an increase in fluids and energy substances surrounding the myofibrils contained in muscle fibers. The fluids include ATP, glycogen, creatine phosphate and water which increase the volume within a cell to create more space between muscle fibers. 

This form of hypertrophy supports overall visual muscle size which is less conducive to overall muscle strength increase and function. It’s believed that bodybuilders benefit most from sarcoplasmic hypertrophy because strength is not needed to support the increase in muscle size. 

Myofibrillar Hypertrophy

myofibrillar hypertrophy occurs from myofibrils (long strands in skeletal muscle which contracts) splitting off and forming more contractile proteins within a muscle fiber. This type of hypertrophy is supposedly better for strength athletes as it is conducive to more strength output (Contractile units) rather than purely muscle growth.

The increase in contractile units makes for a more functional muscle which is typically why strength athletes don’t need to have as much total muscle mass. Although, they still have a decent amount of overall size if training using higher rep ranges as well. 

How does hypertrophy work?

When you weight train, you’re basically tearing down your muscle fibers and hypertrophy occurs as a result of different factors such as anabolic levels, nutrition, and optimum recovery and nuclei. This is known as myofibrillar hypertrophy as explained above.

Science has shown that the muscle fibers increase in volume as a result of myonuclei (Control centers of muscle fibers) multiplication within muscle fibers.

How much muscle you can grow depends on your myonuclei count. Myonuclei are formed from satellite cells that provide nuclei to the muscle for repair after a tough training session.

How do you increase myonuclei?… By progressively increasing damage to the muscles. So in other words, more training volume should promote more nuclei in the muscles.

The other form of hypertrophy (sarcoplasmic) occurs when the fluids within a muscle fiber increases while the fibers do not increase in size as much. 

Both forms of hypertrophy would have to occur though, regardless of if you train more for strength or muscle mass. However, the ratio of myofibril to sarcoplasmic increase will obviously be different between two individuals with a different training focus. 

Who Can Benefit from Hypertrophy?

The short answer is… Everyone can!

Who doesn’t want increased strength and muscle growth? Well, probably people that enjoy having little muscle mass… and there’s nothing wrong with that!

Strength athletes – Training style is important for a strength athlete (In the case that science is correct about the theory of myofibril hypertrophy). That is why strength and power athletes can (Potentially) benefit more from myofibrillar hypertrophy training (reps of 3-6).

A strength athlete relies on muscle density and contractile units used to recruit more muscle fibers.

Bodybuilders – Muscle growth is the goal of every bodybuilder. Although they can greatly benefit from myofibrillar hypertrophy (and they do), the scientific reasoning behind sarcoplasmic hypertrophy is more conducive to overall visible muscle mass.

Once again, sarcoplasmic hypertrophy has not been proven as an exact science. However, someone seeking size gains would benefit from a similar (Or exact) scientific theory of training in such a manner.

Get Fitter, Faster

Level Up Your Fitness: Join our 💪 strong community in Fitness Volt Newsletter. Get daily inspiration, expert-backed workouts, nutrition tips, the latest in strength sports, and the support you need to reach your goals. Subscribe for free!

Please wait...
You're In! Let's Crush Your Fitness Goals Together

Expect expert-backed workouts, nutrition advice, the latest in strength sports, and a whole lot of motivation heading your way.

Old School Bodybuilders
Old School Bodybuilders

What Are The Benefits of Hypertrophy?

There are so many benefits to hypertrophy that we can name the most important few… So we’ll do just that if you were wondering what you can expect from a hypertrophy training program…

  • Increased muscular development
  • Decreased chances of injury
  • More strength and power

Muscle growth is an obvious benefit as the physical aspect of it is highly sought after by many gym-goers and athletes alike.

Hypertrophy prevents injuries as motor learning and aerobic/anaerobic are improved which promotes better muscular functioning.

For power athletes, hypertrophy is extremely beneficial for performing at a high level as a result of better power output. These same athletes can benefit greatly from adopting some sarcoplasmic training as well.

Moderate reps and resistance can increase muscle size, strength and it can prepare an athlete for advanced training. Higher reps may allow for better nutrient transfer to muscle cells, injury prevention, and improved functional muscle tissue capacity.

These benefits have long been discussed and are believed to be why bodybuilders (Or anyone training for mass) experience the amount of size gains that they do.

The “pump” may not allow for hypertrophy to occur on its own but the shuttling of nutrients from increased blood flow is acknowledged as a large contributor to muscle growth.

Are There Negatives to Specific Hypertrophy Training?

There are negatives to everything and hypertrophy is no different (Although the positives outweigh the negatives tenfold).

A strength athlete’s maximal power output can significantly decrease when using higher reps and little rest in between sets (The reason why low reps are best for maximum strength). Maximum energy resources must be reserved for short and heavy bursts of power. So this makes complete sense for a powerlifter to stick with low reps and long rest periods which are most beneficial.

On the other hand, a bodybuilder or someone focusing on mass-building may not see the desired results by sticking with a low rep range and focusing only on strength. Overall training volume and muscle stimulus are essential for maximizing a muscles’ visual size.

Not to mention, varying rep ranges may target specific muscle fibers (slow and fast-twitch) and we all know a bodybuilder needs all the muscle development they can get. But slow-twitch fibers especially, are more conducive to endurance through ATP (provides cell energy) utilization which is necessary for higher volume training (1)

How To Train For Sarcoplasmic and Myofibrillar Hypertrophy

Based on the information we have on the two different kinds of hypertrophy, you might benefit from discipline-specific training. 

Strength – Explosive, low rep (1-5) training for maximum strength/power benefit. Rest 3-5+ minutes in between sets for maximum power output since you’ll be doing mostly compound exercises.

Size – Utilize various rep ranges sticking mostly within the 8-12 rep range for optimal size gains. Rest periods should be shorter (30 seconds – 1 minute, 30 seconds) to challenge the slow-twitch muscle fibers. 

Johnnie Jackson And Branch Warren
Johnnie Jackson And Branch Warren

It’s ok to use both training methods for a hypertrophy goal but it’s more beneficial to focus on one for maximum results. Now again, keep in mind that muscle growth isn’t an exact science but real-world experience has shown us the difference between training for a specific purpose. 

Not to mention, diet also plays a big role in body composition which is usually different between bodybuilders and powerlifters. So there are other factors to consider as well when comparing the effects of both hypertrophy types.

Wrapping Up

You now understand what hypertrophy is and the process. When we workout, we are encouraging hypertrophy whether it be in the form of sarcoplasmic or myofibrillar.

Chris Cormier, Paul Dillett & Nasser El Sonbaty
Chris Cormier, Paul Dillett & Nasser El Sonbaty

It’s a complex process but at the same time, we have come a long way in how we understand the concept of muscular growth and strength.

Regardless of your training preferences, we all strive for our own ideal of physical capability.

The two types of hypertrophy we’ve discussed (Sarcoplasmic and Myofibrillar) need to be tested and researched on a more long term basis to understand the potential mechanism behind each one. Until then, we only have the information that is currently available, based on scientific hypothesis and evidence.

But hypertrophy should still be the goal either way as the benefits are undeniable!

Frequently Asked Questions

What is muscle hypertrophy?

Muscle hypertrophy refers to the increase in muscle size through resistance training which focuses on progressive overload to elicit a growth response.

What causes muscle hypertrophy?

Muscle hypertrophy or growth can occur in a few different ways which are…

Sarcoplasmic hypertrophy – the sarcoplasm increases in size within a cell to create more space between muscle fiber. This form of hypertrophy supports overall visual muscle size. This theory of muscle growth is not a sure science.

myofibrillar hypertrophy – occurs from myofibrils splitting off and forming more contractile units with a muscle fiber. This type of hypertrophy is supposedly better for strength athletes as it is conducive to more strength output (Contractile units).

How to train for hypertrophy?

Hypertrophy can occur using any rep range. However, it’s generally accepted that the 8-12 rep range elicits the best gains due to the ideal combination of resistance and time under tension.

What are the benefits of hypertrophy training?

The benefits of hypertrophy training are increased muscle size and strength, improved physical appearance (aesthetics), better physical performance, a healthier body, and numerous mental benefits.

References

  1. What Is Hypertrophy? – Definition, Causes, Symptoms & Treatment https://study.com/academy/lesson/what-is-hypertrophy-definition-causes-symptoms-treatment.html
  2. Nosaka K, Newton M. Repeated Eccentric Exercise Bouts Do Not Exacerbate Muscle Damage and Repair. J Strength Cond Res. 2002 Feb;16(1):117-122.
  3. Nosaka K, Newton M. Concentric or eccentric training effect on eccentric exercise-induced muscle damage. Med Sci Sports Exerc. 2002 Jan;34(1):63-9.
  4. Drummond, M.J., Fry, C.S., Glynn, E.L., Dreyer, H.C., Dhanani, S., Timmerman, K.L., Volpi, E. and Rasmussen, B.B., 2009. Rapamycin administration in humans blocks the contraction‐induced increase in skeletal muscle protein synthesis. The Journal of physiology, 587(7), pp.1535-1546.
  5. “Hypertrophy.” Strength & Conditioning Research, 30 Sept. 2018, www.strengthandconditioningresearch.com/hypertrophy/
  6. Proske U, Morgan DL. Muscle damage from eccentric exercise: mechanism, mechanical signs, adaptation and clinical applications. J Physiol. 2001 Dec 1;537(Pt 2):333-45.
  7. Nosaka K, Newton M, Sacco P. Responses of human elbow flexor muscles to electrically stimulated forced lengthening exercise. Acta Physiol Scand. 2002 Feb;174(2):137-45.
  8. Nosaka K, Sakamoto K, Newton M, Sacco P. How long does the protective effect on eccentric exercise-induced muscle damage last? Med Sci Sports Exerc. 2001 Sep;33(9):1490-5.
  9. McHugh MP, Connolly DA, Eston RG, Gleim GW. Exercise-induced muscle damage and potential mechanisms for the repeated bout effect. Sports Med. 1999 Mar;27(3):157-70.
  10. Allen DG. Eccentric muscle damage: mechanisms of early reduction of force. Acta Physiol Scand. 2001 Mar;171(3):311-9.
  11. Mero, A., Leikas, A., Knuutinen, J., Hulmi, J.J. and Kovanen, V., 2009. Effect of strength training session on plasma amino acid concentration following oral ingestion of leucine, BCAAs or glutamine in men. European journal of applied physiology, 105(2), p.215.
  12. Clarkson PM. Eccentric exercise and muscle damage. Int J Sports Med. 1997 Oct;18 Suppl 4:S314-7.
  13. Paddon-Jones D, Abernethy PJ. Acute adaptation to low volume eccentric exercise. Med Sci Sports Exerc. 2001 Jul;33(7):1213-9.
  14. Nosaka K, Clarkson PM. Influence of previous concentric exercise on eccentric exercise-induced muscledamage. J Sports Sci. 1997 Oct;15(5):477-83.
  15. Carson JA. The regulation of gene expression in hypertrophying skeletal muscle. Exerc Sport Sci Rev. 1997;25:301-20.
  16. Lieber RL, Friden J. Mechanisms of muscle injury after eccentric contraction. J Sci Med Sport. 1999 Oct;2(3):253-65.
  17. Nosaka K, Clarkson PM. Muscle damage following repeated bouts of high force eccentric exercise. Med Sci Sports Exerc. 1995 Sep;27(9):1263-9.
  18. Nosaka K, Sakamoto K, Newton M, Sacco P. The repeated bout effect of reduced-load eccentric exercise on elbow flexor muscle damage. Eur J Appl Physiol. 2001 Jul;85(1-2):34-40.
  19. Goldberg, A.L., Etlinger, J.D., Goldspink, D.F. and Jablecki, C., 1975. Mechanism of work-induced hypertrophy of skeletal muscle. Medicine and science in sports, 7(3), pp.185-198.
  20. Bodine, S.C., Stitt, T.N., Gonzalez, M., Kline, W.O., Stover, G.L., Bauerlein, R., Zlotchenko, E., Scrimgeour, A., Lawrence, J.C., Glass, D.J. and Yancopoulos, G.D., 2001. Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nature cell biology, 3(11), pp.1014-1019.
  21. Atherton PJ, Etheridge T, Watt PW, Wilkinson D, Selby A,Rankin D, Smith K & Rennie MJ (2010). Muscle full effect after oral protein: time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signaling. Am J Clin Nutr 92, 1080–1088. 

If you have any questions about this article, please feel free to contact Matthew Magnante by leaving a comment below.

Stay on top of the latest fitness news and updates by adding Fitness Volt to your Google News feed: Follow us on Google News You can also follow us on Twitter, Facebook, Instagram, and YouTube for even more content.
Facebook Twitter Reddit Flipboard LinkedIn Pinterest
Categories: Featured Muscle Science Muscle-Building
Previous Post

Dorian Yates Hits Kettlebells With Intense At-Home Workout

Next Post

Dexter Jackson Tears Into Shawn Ray: ‘I Would Definitely Smoke Him!’

Matthew Magnante, ACE

Matthew Magnante, ACE

Matthew is an ACE (American Council On Exercise) certified fitness professional who has had a passion for fitness since elementary school and continues to research and learn how to build muscle effectively through training and diet. He also loves to help others to achieve their fitness goals and spread the knowledge where needed. Matthew's other passions include learning about mindfulness, strolling through nature, traveling, and always working to improve overall.

Related

Pause and Squeeze Method
Training

The 3-Second ‘Pause & Squeeze’ Trick That Explodes Muscle Growth

Nick Walker
Bodybuilding

Nick Walker Destroys High-Volume Rest-Pause Hypertrophy Push Workout 4 Weeks Before 2025 Mr. Olympia

More Weight Or More Reps
Training

More Weight vs. More Reps: The Definitive Answer That Will Change Your Workouts Forever

Intensity Extenders Muscle Growth
Training

Beyond Failure: 3 “Intensity Extenders” Pro Bodybuilders Use to Spark New Muscle Growth

Mechanical Drop Set
Training

The Mechanical Drop Set Masterclass: How to Grow Muscle Without Changing Weights

Eccentric Overload Protocol
Training

The “Eccentric Overload” Protocol: I Slowed Down My Reps for 4 Weeks – Did My Strength Explode?

Comments 1

  1. Avatar Dafina Berisha says:
    7 years ago

    Hello!
    I am 22 years old, getting overweight these last months I think, and I don’t really know the reason why?!
    I need to lose weight and I need fast because I just need that I want my healthy life back… I tried fitness It didn’t really help..
    Btw I saw this website and for me it looked a nice one and a real product to lose weight fast and also very healthy..
    Can someone check it or give it a review for me?! Thnx

    Reply

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Latest

Jay Cutler Weighs In on Shaun Clarida’s Bid to Compete in Two Divisions at the 2026 Mr. Olympia

Farhanna Farid (U52KG) Sets 217.5-kg (479.5-lb) Raw Deadlift IPF World Record at 2025 Asian Open Powerlifting Championships

Terrick El Guindy Says If Andrew Jacked Adds 5 Lbs of Muscle and Comes in Peeled, ‘It’s Over’ at 2026 Mr. Olympia

Tom Platz Reveals How to Break Training Plateaus

Video: 55-Year-Old Weightlifter Dies After Horrific Bench Press Accident

Joe Rogan, Derek MPMD Say Old-School Bodybuilders Were ‘Deceptive’: “They Couldn’t Admit They Were on Gear’

Fitness Volt

At Fitness Volt, our mission is to empower every individual on their fitness journey by providing expert advice, the latest research, and comprehensive resources. Whether you are a beginner or an elite athlete, we are here to support your goals with trustworthy and up-to-date information in strength, fitness, and nutrition. Read more.

For inquiries, please contact us at:
Email: [email protected]

About Us | Careers | Contact Form

Topics

  • Mr. Olympia
  • Bodybuilding
  • Strongman
  • WSM
  • Powerlifting
  • CrossFit
  • Workouts
  • Exercises
  • Training
  • Reviews
  • Nutrition
  • Discussion Forum

More

  • Calculators
  • Fasting
  • Mastering The Deadlift
  • Workout Plans
  • At-Home Workouts
  • Programs
  • Supplements
  • Newsletter
  • Review Process
  • Accessibility
  • Advertise
  • Syndication
  • Sitemap
  • DMCA
  • Copyrights
  • Terms
  • Privacy
  • Cookies
  • Disclaimer

© Copyright 2010 - 2024 Fitness Volt IBC. All Rights Reserved.

No Result
View All Result
  • News
    • Bodybuilding
    • Powerlifting
    • Strongman
    • Armwrestling
    • CrossFit
    • Results
    • Arnold Classic
    • Mr. Olympia
    • 2025 WSM
  • Forum
  • Workouts
    • Training
    • Workout Plans
    • Muscle Groups
    • Celebrity Workouts
    • Programs
    • Mastering The Deadlift
  • Exercise Guides
    • Arms
    • Back
    • Chest
    • Core
    • Legs and Glutes
    • Shoulders
    • Yoga
  • Nutrition
    • Diet
    • Fasting
    • Diet Plans
    • Supplements
    • Nutrition Tips
    • Reviews
    • Food Facts
  • Fitness Calculator
  • More
    • DIY
    • Strength Standards
    • Motivation
    • Videos

© Copyright 2010 - 2024 Fitness Volt IBC. All Rights Reserved.